How does the carburetor actually work?
Throttle response/transition right off idle?
Cruising at varying vehicle speeds at very light throttle.
Heavy part throttle only?
Transition to full throttle?
Power at full throttle?
I ALWAYS tune for results first and start with idle mixture and "heavy part throttle".
This establishes whether or not I have the idle system up to par for the application, and that I'm using the correct main jet for it as well.
Once the idle system is correct, and correct main jet, tuning the "part throttle" via the APT/primary metering rods, and WOT with hangers, air door settings and secondary metering rods is relatively easy.
Don't forget timing either, the distributor is equally as important as the carburetor, and the more timing you add when the engine wants/needs it, the LESS fuel you will need from the carburetor. The carburetor by design is also a "load sensing" device, and it will vary A/F based on engine requirements, throttle angle, air flow past the venturi, and pressure differentials above and below the venturi.
Two other load sensing devices are the distributor vacuum advance and the power piston. The distributor mechanical advance is engine speed controlled, and a player here as well.......Cliff