Best idle quality at the leanest setting(s). Pretty much covered that in my first two responses.
Keep in mind that folks tend to associate "lean" with "efficient", like it's going to run better and get better fuel economy, etc.
Lean fuel mixtures are incredibly difficult to burn, and a LOT of noxious pollutants will exit your tailpipes if you venture toward lean settings for any particular combination(s) of parts.
Most vehicles these carburetors are used on will NOT have all of the factory emission equipment in place and operational.
If we set up 100 carburetors in the shop for these older vehicles, at most there will be one or two that are still "stock". Folks change a LOT of parts out, in search of improved performance. The catalytic converters get removed, factory intakes gone, EGR plugged off, cooler thermostats, blocked exhaust crossovers, air pumps amputated, aftermarket intakes installed, "high performance camshaft, etc, etc.
In any and all cases, when it comes to setting the carburetor idle mixture screws, set them so the engine idles the smoothest and is happy for the combination of parts being used. This usually ends up at or very close to "lean drop" for most applications. Many heavily cammed engines will not like being anywhere near "lean" at idle, and tend to like a lot of timing and a lot of fuel at idle to be happy. The closer the engine is to "stock, the happier it will be with leaner idle fuel setting(s), as a general rule......Cliff