You will find the Holley carb (no mention as to part number, model, mods made to it or type of boosters used) more difficult to tune for part throttle A/F than the Q-jet.
You will NOT find your results changing jets and PV's. A large portion of the fuel at part throttle comes from the transfer slots as the large primary bores and inefficient booster design aren't in the mix like they are on the Q-jet.
I remember my early tuning efforts with Holley carburetors dating clear back to the 1970's. I remember locking the emergency brake and blocking the tires, putting the car in gear, then climbing up and bracing myself over the carb, looking down in it and watching for fuel to start streaming from the boosters as I applied load to the engine against the converter.
NOTHING....WTF? ALL the fuel was coming from the idle discharge holes and transfer slots, not the first drop from the boosters. The Q-jets I was tuning at the time, or attempting to tune as it was all a new game for me had TONS of fuel coming from the boosters in a nice cone shaped well atomized pattern with the slightest movement of the throttle off idle.
Hum? An early lesson in Holley tuning and by that time I had worn the bowl thread clear out of the main casting changing jet sizes in vain to try to get some decent fuel economy out of them. Not having any luck sent me into the air bleeds and then into the metering blocks. I got good at them early on then really good at them after a decade or so of tuning them to the brink of extinction.
By design I was never able to equal the Q-jet or the TQ's in fuel economy and seamless transition right off idle and for normal driving, but any heavy throttle movements without the secondaries was very impressive in comparison. This simply happens due to the much greater CFM available w/o having to get into the secondaries like I did on the spread bore units.
In later years I played around more with the larger annular booster Holley carbs and found them to be better in that area, but it comes at a cost of CFM lost stuffing a much larger booster into the larger bores.
I finally decided to pick a direction and run with it, so in 2003 when I went full time into the carburetor rebuilding/restoration business I dropped just about everything from the list and stuck almost 100 percent with Q-jets, but would take in a factory Tri-Power set-up (2-JETS) on occasion. That didn't last long and very quickly my backlog went out past two years. So I dropped everything but Q-jets, hired more help and we ran full time till a couple of years ago. Most of my employees moved on, I did not replace any of them as it became a perfect opportunity to retire and not have to put anyone on the street.
There's the short version of a long story but at this time I'm only selling parts, rebuild kits, and custom rebuild kits with tuning parts. I have the best accl pump seals currently available and NOTHING will make them swell up like the cheap soft light blue seals showing up from all the other sources.........Cliff
https://cliffshighperformance.com/simplemachinesforum/index.php/topic,4546.0.html