There are a few drawbacks using a Marine carb in an automotive application. They lack vacuum ports for the distributor, and are set up for a Marine application.
Marine engines are heavily loaded most of their lives, so require a LOT more fuel than an automotive engine.
You can add a vacuum port for the distributor, and recalibrate for the engine you've built. Going to need a good bit of idle fuel as that cam is pretty "hefty" for 350cid at that compression ratio, and tight LSA, so it's going to have a "weak" signal at idle speed.
We can help out with everything you need to build the carb and set it up for what you are doing, no problem there.....Cliff